Facing an unplanned pregnancy can feel overwhelming, often leading to quick decisions driven by fear or pressure. If you want to continue your pregnancy after taking mifepristone, abortion pill reversal may be right for you.
How Does Abortion Pill Reversal Work?
Abortion pill reversal aims to counteract the effects of mifepristone, the first dose in the abortion pill regimen. The reversal protocol is for those who have ONLY taken the first drug (mifepristone).
Abortion pill reversal treatment involves prescribing natural progesterone supplements to restore hormone levels, potentially allowing the pregnancy to continue. Natural progesterone competes with mifepristone for receptor sites. This helps the embryo stay attached to the uterus and continue to grow.[1]
After you start the treatment, your healthcare professional will schedule an ultrasound to see if the pregnancy is progressing. You will continue to take the progesterone until you start prenatal care.
When Should You Start the Treatment?
For the best results, begin reversal treatment within 24 hours of taking mifepristone.[2]
However, there have been successful cases within 72 hours of taking mifepristone. If you are uncertain if too much time has passed, you can still contact the Abortion Pill Reversal Network to get help.
For 24/7 support, contact the Abortion Pill Reversal Network’s helpline at (877) 558-0333 or email help@apr.life.
Success Rates
Initial studies have shown that 68% of pregnancies treated with oral progesterone progressed normally to full term.[3] However, results may vary.
Side Effects & Risks
Even though progesterone is a natural hormone, you may still experience side effects from the treatment, including[4]:
- Lack of energy
- Slight dizziness or lightheadedness
- Mild headaches
- Muscle aches
- Bloating
- Diarrhea
- Spotting or light vaginal bleeding (from the abortion drug)
- Mild cramps (from the abortion drug)
- Symptoms associated with pregnancy (breast tenderness, fatigue, mild nausea and vomiting, moodiness, frequent urination)
- The progesterone fails to rescue the pregnancy
Note: Some forms of progesterone contain peanut oil. If you have a peanut allergy, tell your doctor before starting the reversal process. They can prescribe a different type of progesterone.
What If You Have Taken Mifepristone and Misoprostol?
The abortion pill protocol is not always 100% effective, even after taking both mifepristone and misoprostol. Even if you have taken both drugs, there may still be an intact growing pregnancy.
Receive a free ultrasound at Caldwell Pregnancy Care Center to learn if your pregnancy is still viable. Contact us to get help today.
How Much Does the Treatment Cost?
The cost of your treatment depends on the type of progesterone your doctor prescribes and your insurance coverage. In cases of financial hardship, the Abortion Pill Reversal Network will help you find ways to reduce the cost of the treatment.
Learn More About Abortion Pill Reversal at Caldwell Pregnancy Care Center
You aren’t in this alone. Caldwell Pregnancy Care Center is here to help you explore all of your pregnancy options, so you can make an informed and empowered decision!
If you’ve already taken the first abortion pill, time is of the essence. Contact the Abortion Pill Reversal Network’s 24/7 helpline at (877) 558-0333 or email help@apr.life to start the reversal process now!
Please be aware that Caldwell Pregnancy Care Center does not provide or refer for abortion services.
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Frequently Asked Questions
Is abortion pill reversal safe?
Yes. Doctors have safely used natural progesterone during pregnancy for over 50 years.[5]
When administered and monitored by qualified healthcare professionals, abortion pill reversal carries minimal risk.[3]
Will my baby be healthy if the reversal works?
Current studies show no increased risk of birth defects in babies born after successful abortion pill reversal.[3]
Note that researchers conducted these studies in women who had only taken mifepristone.
What if I live in a different state?
The Abortion Pill Reversal Network can connect you with healthcare professionals nationwide, including telemedicine options where legally permitted.
Sources
- Delgado G, Davenport ML. Progesterone use to reverse the effects of mifepristone. Ann Pharmacother. 2012;46(12):e-pub ahead of print. https://stenoinstitute.org/wp-content/uploads/2025/08/Article-Annals-of-Pharmacotherapy-APR.pdf
- Frequently Asked Questions. Abortion Pill Reversal. (n.d.). https://www.abortionpillreversal.com/abortion-pill-reversal/faq
- Delgado, G., Condly, S. J., Davenport, M., Tinnakornsrisuphap, T., Mack, J., Khauv, V., & Zhou, P. S. (2018). A case series detailing the successful reversal of the effects of mifepristone using progesterone. Issues in law & medicine. https://pubmed.ncbi.nlm.nih.gov/30831017/
- Mayo Clinic. (2025, November 1). Progesterone (oral route) – Side effects & dosage. https://www.mayoclinic.org/drugs-supplements/progesterone-oral-route/description/drg-20075298#drug-side-effects
- Dante G, Vaccaro V, Facchinetti F. Use of progestagens during early pregnancy. Facts Views Vis Obgyn. 2013;5(1):66-71. PMID: 24753930; PMCID: PMC3987350.


